Epidemiological and histopathological aspects of ocular melanomas in Northeastern Romania

Vol. 65 No. 1, 2024

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Claudia Florida Costea, Andrei Ionut Cucu, Gabriela Florenta Dumitrescu, Anca Sava, Gabriela Dimitriu, Tina Botoc, Mihaela Roxana Popescu, Catalin Mihai Buzduga, Ana Maria Dumitrescu, Alexandra Starica, Georgiana Macovei, Iulian Prutianu, Laurentiu Andrei Blaj, Daniela Maria Tanase, Dragos Viorel Scripcariu

Ocular melanoma is a rare but complex disease in current medical practice. Our retrospective study spans over a period of 28 years and analyzed uveal and conjunctival melanomas that were consecutively admitted, diagnosed, and treated in the 2nd Ophthalmology Clinic of Prof. Dr. Nicolae Oblu Emergency Clinical Hospital, Iasi, Romania. The patients were selected from the records of the Department of Pathology of our Hospital, being diagnosed by standard histopathological techniques. The aim of this study was to summarize the epidemiological and pathological aspects of uveal and conjunctival melanomas in Northeastern region of Romania. In our study, we did not notice a predilection of uveal and conjunctival melanoma to one particular gender. The most common histological subtypes of ocular melanomas were the heavily pigmented spindle cell subtype, followed by the epithelioid subtype. Our patients sought medical help in a timely manner, before the systemic invasion of the disease could develop.

Corresponding author: Andrei Ionut Cucu, MD, PhD; e-mail: andreiucucu@yahoo.com; Catalin Mihai Buzduga, Professor, MD, PhD; e-mail: buzdugacatalin@yahoo.com

DOI: 10.47162/RJME.65.1.05 Download PDF
Download cover
Download contents

Journal archive