Incidental case of primary renal lymphoma (PRL) in a patient with chronic hepatitis C infection. Report of a rare case

Vol. 61 No. 3, 2020

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Mircea Litescu, Ion Daniel Baboi, Laura Paverman, Camelia Doina Vrabie, Niculae Iordache, Ionut Simion Coman, Corina-Veronica Lupascu-Ursulescu, Ion Dina, Valentin Titus Grigorean

Chronic viral hepatitis C (CHC) is a global health problem, being responsible for about 399 000 deaths worldwide, mostly from cirrhosis and hepatocellular carcinoma. Virus C infection has well known hepatic manifestations - cirrhosis and liver cancer - but the extrahepatic ones are responsible for up to 75% of morbidity in these patients. The well-known hepatitis C virus (HCV) lymphotropism is probably linked with the most frequent extrahepatic manifestations, mixed cryoglobulinemia and B-cell non-Hodgkin s lymphoma (BCNHL). We report a very rare entity, the case of an 82-year-old female with Child-Pugh class A viral C cirrhosis associated with a primary renal lymphoma (PRL). PRL is a non-Hodgkin s lymphoma (NHL) localized in the kidney, without any involvement of extrarenal lymphatic tissue. In addition to the case report, some relevant data from the literature were reviewed here.

Corresponding author: Laura Paverman, MD, PhD Student; e-mail: laura.paverman@drd.umfcd.ro; Corina-Veronica Lupascu-Ursulescu, Associate Professor, MD, PhD; e-mail: corina.ursulescu@umfiasi.ro

DOI: 10.47162/RJME.61.3.33 Download PDF
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