The bursa of Hieronymus Fabricius ab Aquapendente: from original iconography to most recent research

Vol. 61 No. 2, 2020


Domenico Ribatti, Andrea Porzionato, Aron Emmi, Raffaele De Caro

Hieronymus Fabricius ab Aquapendente (1533-1619) described the homonymous bursa in the De Formatione Ovi et Pulli, published posthumously in 1621. He also included a figure in which the bursa was depicted. We here present the figure of the bursa of Fabricius, along with corrections of some mislabeling still presents in some anastatic copies. The bursa of Fabricius is universally known as the origin of B-lymphocytes; morphogenetical and physiological issues are also considered.

Corresponding author: Domenico Ribatti, Professor, MD, PhD; e-mail:; Raffaele De Caro, Professor, MD, PhD; e-mail:

DOI: 10.47162/RJME.61.2.31 Download PDF
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