Type II pleuropulmonary blastoma in a 2-year-old girl: a case report
Vol. 60 No. 4, 2019
ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY
Teodora Smaranda Arghirescu, Ada Maria Carstea, Licinia Andrada Oprisoni, Elena Rodica Heredea, Ovidiu Nicolae Burlacu, Ioana Delia Horhat, Calin Marius Popoiu
Pleuropulmonary blastoma (PPB) is a very rare, malignant aggressive primary lung tumor, which occurs mainly in children less than 5 years old. Due to its poor prognosis, it is aggressively treated with multimodal therapy including surgery and chemotherapy. We present a case of PPB in a 2-year-old girl who was brought to the pediatric clinic for fever, cough and respiratory distress. Imaging studies showed a heterogeneous solid-cystic mass (12/9/11 cm) in the upper right pulmonary lobe. Through right thoracotomy, a specimen was obtained, the histopathological and immunohistochemical features of the specimen being suggestive for type II PPB. Aggressive chemotherapy and right pneumonectomy resulted in control of disease, the patient being currently in complete remission four years after the diagnosis.
Corresponding author: Teodora Smaranda Arghirescu, Associate Professor, MD, PhD; e-mail: sarghirescu@yahoo.com; Ioana Delia Horhat, MD, PhD; e-mail: deliahorhat@yahoo.com
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