Cutaneous melanoma arising on pre-existing nevi - case reports

Vol. 60 No. 3, 2019


Ioana Mihaela Dogaru, Natalia Dumitrescu, Ana Maria Oproiu, Cristian Radu Jecan, Mariana Costache, Oana Maria Patrascu, Ioan Petre Florescu

Skin cancer is a common healthcare issue that affects millions of people worldwide. Only a small part of that population is suffering from melanoma and an even smaller proportion has melanoma developed on a pre-existing nevus. This paper illustrates five such cases, diagnosed over an 18-month period, with their histological particular aspects. Among the total number of patients diagnosed and treated in the Department of Plastic and Reconstructive Surgery, University Emergency Hospital, Bucharest, Romania, over approximately one year, of which half for melanoma in general or for benign nevi, only a small fraction had developed melanoma on a common or dysplastic nevus. These patients, as well as those with de novo developed melanoma, are a reason for concern since most of the lesions were diagnosed in a locally advanced stage of the disease. Though efforts are being made to screen and diagnose early, there are still a lot to be done in order to lower the mortality and morbidity rates for this pathology.

Corresponding author: Ana Maria Oproiu, Associate Professor, MD, PhD; e-mail:

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