Pathological fractures of humerus in children. Therapeutic and pathological considerations

Vol. 60 No. 3, 2019


Maria Daniela Trailescu, Adrian Ionel Pavel, Mircea Alexandru Pop, Nicoleta Zurbau-Anghel, George Alin Stoica, Radu Florin Fruntelata, Cristina Elena Singer, Maria Stoica, Cristian Constantin

Introduction: A pathological fracture appears after a low-energy trauma or minor trauma on bones with a modified histological structure; sometimes, the patient reports shoulder pain antedating the fracture. The most common benign bone tumors that cause pathological fractures in children are simple bone cysts, aneurysmal bone cysts, non-ossifying fibromas and fibrous dysplasia. This type of bone tumors is usually asymptomatic until they reach a large size and cause a pathological fracture after minor trauma. The optimal treatment remains controversial. Our objective was to describe our modern treatment strategies of the large benign osseous tumors of the humerus complicated by pathological humerus fractures and histological aspects in these cases. Patients, Materials and Methods: The study was prospective and included patients who were diagnosed with pathological humeral fractures, which required surgically orthopedic treatment. We selected three cases of pathological fractures of humerus in children each with its particularities, treated in the Department of Pediatric Surgery and Orthopedics, Emergency County Hospital, Arad, Romania. Treatment included curettage of the cyst, sampling for histopathological (HP) examination, bone substitution and titanium elastic nails (TEN) osteosynthesis. Results: No complications and no recurrence were seen in the early postoperative period. Conclusions: Osteosynthesis with TEN and bone substitution is a viable option for treatment of pathological fracture of humerus, secondary to the osseous benign tumors, which required surgically treatment, despite the different HP aspects. By using a combined treatment in these cases, we eliminate the disadvantages of isolated use of the described techniques in the literature.

Corresponding author: Maria Stoica, Senior Lecturer, MD, PhD; e-mail:; Cristina Elena Singer, Senior Lecturer, MD, PhD; e-mail:

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