Craniofacial morphology aspects in children with isolated growth hormone deficiency - a cephalometric study

Vol. 60 No. 2, 2019


Smaranda Adelina Preda, Dana-Maria Albulescu, Mihaela-Roxana Mitroi, Mihaela Popescu, Florina Nechita, Adrian Camen, Ioana Adina Cotoi

Craniofacial and dental morphology is influenced by different circulating hormones, but it is of particular importance that there is growth hormone (GH) in normal craniofacial and teeth development. Craniofacial morphometry studies in children with GH deficiency show different changes in certain anthropometric variables in the sense of reducing their values compared to normal children s developmental norms in different stages of childhood and adolescence. Therefore, the early establishment of GH replacement therapy can correct craniofacial morphological changes induced by GH deficiency. In our study, we evaluated different anthropometric craniofacial variables at children with GH deficiency and we established some anthropometric and morphological characteristics associated with this pathology.

Corresponding author: Adrian Camen, Associate Professor, DMD, PhD; e-mail:; Florina Nechita, Lecturer, PhD; e-mail:

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