Rare benign tumor of the larynx - laryngeal amyloidosis

Vol. 59 No. 4, 2018

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Ioana Delia Horhat, Nicolae Constantin Balica, Horatiu Constantin Urechescu, Flavia Baderca, Marioara Poenaru, Caius Ion Doros, Ion Cristian Mot, Eugen Radu Boia, Carmen Aurelia Mogoanta, Alexandru Chioreanu, Alexandru Nicolae Vlaescu, Cristian Andrei Sarau

We report a case of rare benign tumor of the larynx - amyloidosis of larynx - in a 52-year-old female who presented to the Department of Ear, Nose and Throat (ENT), Timisoara Municipal Hospital, Romania, with dysphonia. The patient s first presentation was in June 2012, with a polypoid formation localized on left vocal cord. The patient underwent a suspended microlaryngoscopy (SM) with tumor removal followed by histopathological examination, which revealed a laryngeal amyloidosis. The tumor recurred in 2013, 2014, 2016, 2017 and 2018. The patient underwent tracheotomy, followed by SM with endoscopic CO2 laser procedures, in order to remove the tumor and to ensure the airway. The follow-up was for six years. In May 2018, amyloid was located in subglottis, glottis and left false vocal fold. The patient needed five revision surgical procedures. The patient did not developed systemic amyloidosis during the follow-up period.

Corresponding author: Flavia Baderca, Associate Professor, MD, PhD; e-mail: flaviabaderca@yahoo.com; Horatiu Constantin Urechescu, MD, PhD; e-mails: urechescu.horatiu@umft.ro, uhc_83@yahoo.com

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