Diabetic foot - epidemiological and histopathological aspects

Vol. 59 No. 3, 2018

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Marilena Monica Tantu, George Mihail Man, Liliana Marcela Rogozea, Carmen Daniela Domnariu, Florentina Cristina Plesa, Diana-Maria Trasca, Bogdan-Virgil Cotoi, Loredana Elena Stoica, Camelia Nicolae, Roxana Maria Nemes

Our study included a total of 259 patients with diabetes, who were admitted to the Department of Plastic Surgery and Reconstructive Microsurgery of the Emergency County Hospital of Pitesti, Romania, in 2016, with the diagnosis of diabetic foot. Of the 259 patients, 55 (21.23%) were diagnosed with type 1 diabetes, and the remaining 204 (78.77%) were diagnosed with type 2 diabetes; the ratio of type 1/type 2 diabetes was 1/3.7. The injuries presented by the patients were osteitis (27.81%), moist gangrene (21.62%), abscesses (18.92%), cellulitis (11.19%), various forms of fasciitis (8.88%), perforating strand (6.18%), and dry gangrene (5.4%). The disease was most commonly diagnosed in males in the rural environment. Most of the patients were in the age group of 61-70 years old. All patients were surgically treated, but 142 (54.82%) patients needed amputations of foot segments (fingers, metatarsal or tarsal bones). The histopathological and immunohistochemical study on excised fragments revealed the existence of a chronic inflammatory process formed mainly from macrophages, mast cells and CD4+ T-lymphocytes.

Corresponding author: Florentina Cristina Plesa, Assistant Professor, MD, PhD; e-mail: plesacristina@yahoo.com; Bogdan-Virgil Cotoi, Lecturer, MD, PhD; e-mail: bogdan230376@yahoo.ro

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