Diagnostic challenges in a patient with calciphylaxia - a case report

Vol. 59 No. 2, 2018

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Violeta Claudia Bojinca, Mihai Bojinca, Cristina-Ileana Iosif, Serban Mihai Balanescu, Andra Rodica Balanescu

Calciphylaxis is a condition with unclear etiopathogeny with vascular calcifications and thrombotic occlusion that lead to necrotic lesions. It is usually described in patients with end-stage renal disease (ESRD), but also in other conditions. The mortality rate is high, due to sepsis and internal organ failure. We present the case of a patient with multiple comorbidities (ESRD, diabetes, hypertension, Monckeberg s sclerosis) with problems of differential diagnostic due to the necrotic lesions that mislead initially to systemic lupus erythematosus (SLE) with necrotizing vasculitis.

Corresponding author: Mihai Bojinca, Associate Professor, MD, PhD; e-mail: vmbojinca@yahoo.com

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