Neurosurgical rare disease: solitary plasmacytoma of the skull - case report and literature review

Vol. 59 No. 1, 2018


Radu Eugen Rizea, Mihai Popescu, Karina Lidia Gheorghita, George Popescu, Marius Cristian Neamtu, Cristina Jana Busuioc, Alexandru Vlad Ciurea

Solitary extranevraxial plasmacytoma (SEP), as a clinical entity without signs of systemic myelomatosis, is extremely rare; it is difficult to find literature on the issue of patient management and proper course of action in the presence of associated pathology. The authors present a rare case of plasmacytoma of the skull vault associated with severe cardiac pathology, which made surgery extremely difficult and possible only through temporization of the interventions, as presented. We discuss our findings and opportunities for treatment in this case, which seemed unapproachable at presentation, in connection with the associated cardiac pathology. The case was followed-up for eight years with no recurrences.

Corresponding author: Mihai Popescu, Professor, MD, PhD; e-mails:,; Cristina Jana Busuioc, Associate Professor, MD, PhD; e-mail:

Download PDF
Download cover
Download contents

Journal archive