Uteroplacental apoplexy associated with invasive cervical neoplasm

Vol. 58 No. 4, 2017


Anca Daniela Braila, Boris Marinov Krastev, Emilia Mihai-Zamfir, Dragos Cristian Caraveteanu, Nawaf Al Krayem, Mihai Braila, Rodica Velea, Adrian Neacsu

The cervical cancer is the worldwide second neoplasia in women, after the breast cancer. The incidence of invasive carcinoma in pregnancy is 1/2000 to 1/10 000 pregnancies. In most of the studies, almost all the patients had microinvasive carcinoma or limited cervical carcinoma at the cervix level. In the uteroplacental apoplexy, pathologically, retroplacental hematoma is formed while the fetus is still in the uterus. When speaking about the uteroplacental apoplexy, the fetal mortality is 100% and the maternal mortality can reach 5%. The particularity of the presented case is the association of the invasive cervical neoplasm, pathology unknown to the patient, with uteroplacental apoplexy, diagnosis for which she was hospitalized as an emergency. After the extraction of the dead fetus by segmental-transversal cesarean section, we continued to perform the total hysterectomy with adnexectomy. The fetus, the placenta, the uterus and the ovaries were sent for histopathological examination. Subsequently, the histopathological bulletin revealed cervical lesions in the neck of type cervical intraepithelial neoplasia (CIN) I, CIN II, CIN III, metaplastic squamous epithelium and moderately differentiated squamous cell carcinoma.

Corresponding author: Anca Daniela Braila, Lecturer, MD, PhD; e-mail: ancabraila@yahoo.com

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