Carcinogenic uterine risk of repeated abortions: hormone receptors tumoral expression

Vol. 58 No. 4, 2017

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Manuela Stoicescu, Simona Gabriela Bungau, Delia Mirela Tit, Gabriela Mutiu, Anamaria Lavinia Purza, Vasile Ciprian Iovan, Ovidiu Laurean Pop

The main objective of this study is to draw the attention that repeated induced abortions in the women s physiological history are very dangerous and could lead to developing uterine cancer. The legislation regarding this practice is variable in different countries. Relevant information in the field concerning the numerous risk factors that appear with abortions must be taught in schools before girls start their sexual life and can help avoiding the complications that may follow. Also, the abortion should be an extreme measure that must be used only in extreme cases that threaten the mother s life or imply the health of the future child. The study comprised 258 women diagnosed with endometrial carcinoma, without any risks factors for this type of cancer, which were questioned regarding the abortions in previous history. The results show that the age when the uterine carcinoma appears is even lower as the number of abortions is higher and the number of this type of cancer cases is directly proportional with the number of abortions suffered. In order to avoid this fact we have to pay more attention to the legislation and education of the patients. Also, we followed the expression of both estrogen and progesterone hormone receptors, in the case of uterine cancer that occurred in women who had abortions in history compared to the expression of hormone receptors in the case of patients who did not have abortions.

Corresponding author: Vasile Ciprian Iovan, Lecturer, MD, PhD; e-mail: dr.iovan@biostandard.ro; Simona Gabriela Bungau, Professor, PhD, Dr.habil.; e-mail: simonabungau@gmail.com

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