Parotid sclerosing mucoepidermoid carcinoma: a case report and immunohistochemical study

Vol. 57 No. 3, 2016

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Florin-Liviu Gherghina, Adrian Camen, Maria Cristina Munteanu, Claudiu Margaritescu, Calin-Gabriel Sarla

Here we report the case of a 63-year-old female with a parotid sclerosing mucoepidermoid carcinoma diagnosed and treated at the Department of Oral and Maxillofacial Surgery, Emergency County Hospital of Craiova, Romania. The clinical and imaging investigation revealed a parotid malignant tumor with central fluid-filled cystic formation. Histopathology found an intermediate grade sclerosing mucoepidermoid carcinoma that invaded the adjacent adipose and striated muscle tissues, but without perineural and lymphovascular invasion. The immunohistochemistry investigated mainly biomarkers involved in the induction of a local aggressive behavior. This case report describes a rare parotid sclerosing mucoepidermoid carcinoma with peculiar clinical and morphological characteristic features. The immunohistochemical study sustained its intermediate grade malignancy highlighting the prognostic value of some of the used biomarkers.

Corresponding author: Claudiu Margaritescu, Professor, MD, PhD; e-mail: c_margaritescu2000@yahoo.com

Download PDF
Download cover
Download contents

Journal archive