Histological study on effect of Nigella sativa on aged olfactory system of female albino rat

Vol. 55 No. 2 Suppl., 2014
This supplement was not sponsored by Outside Organizations.

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Sohair A. M. Eltony, Sanaa A. M. Elgayar

Nigella sativa (NS) has wide-ranging healing properties, neuroprotective and antioxidant effects. Aging process is commonly associated with a decline in the chemical senses including smell. To detect a possible improvement effect of NS on the aging of the olfactory system we used 15 female albino rats that equally divided into three groups: group I (control adult), group II (control aged), group III (treated aged) received 40 mg/kg/day NS orally for two months. Specimens from the olfactory epithelium (OE), main olfactory bulb (MOB) and piriform cortex (PC) were processed for light and electron microscopy. Aging in OE revealed reduction in thickness, vacuolations, an increase in PAS reaction and lipofuscin autofluorescence. Aged MOB and PC exhibited a reduction in basophilia and accumulation of neurofibrillary tangles (NFTs) in mitral and pyramidal cells respectively. NS treatment improved the structure and the thickness of the OE and reduced the lipofuscin autofluorescence. It also attenuated the reduction in cytoplasmic basophilia and the accumulation of lipofuscin pigment and the NFTs in both mitral and pyramidal cells and the lipofuscin autofluorescence. These observations indicate that use of NS, could be of value in improving the structural changes of the peripheral and central main olfactory organs, which occurred in association with aging.

Corresponding author: Sanaa A. M. Elgayar, Professor, MD, PhD; e-mail: selgar1@hotmail.com

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ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Delia Ioana Ciocan, Dragos Stanciu, Manuela Anca Popescu, Florin Miculescu, Ioan Plotog, Gaudentiu Varzaru, Lucian Toma Ciocan

This study proposed to evaluate the surface morphology of different types of orthodontic brackets and the characteristics of their adhesion to the tooth enamel. There have been taken into study six metallic, five ceramic and one polymeric bracket from different brands (Ormco, Lancer, Leone, Damon, 3M, Ultradent, American Orthodontics, Rocky Mountain). The surface base of the each bracket it have been ESEM analyzed using scanning electron microscope Phillips XL-30 ESEM. There have been investigated several parameters that have a potential influence of the bracket-bonding agent interface joint: chemical composition, roughness, surface morphology and wideness. After ESEM analysis, the same metallic and ceramic brackets have been afterwards collated on extracted teeth and subjected to mechanical tests. After the mechanical testing, the samples were once again ESEM investigated. All fractures occurred in the area of the adhesive system, recording adhesive fractures of the tooth-composite resin and composite-bracket, cohesive fractures and both. The metallic brackets surfaces that are optima for a good adhesion is that of a mesh sand blasted and acid etched. From the esthetic brackets, the ceramic ones are superior to polymeric ones regarding bonding to teeth.

Corresponding author: Delia Ioana Ciocan, Assistant Professor; e-mail: delia_ciocanaru@yahoo.com

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