Anatomo-clinical aspects of the basal cell carcinoma at the level of the cephalic end

Vol. 54 No. 3 Suppl., 2013
This supplement was not sponsored by Outside Organizations.

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Anca Bordianu, I. P. Florescu, Anca Muresan, Elena Bernad, M. Craina, Izabella Sargan

More than one third of all diagnosed cancer cases from all over the world are skin cancers, and the majorities are basal cell carcinomas. The incidence of skin tumors around the world is growing, the main concern being the increased frequency of skin tumors among young persons. Therefore, an early detection is required, starting with the general practitioner, dermatologist, oncologist, plastic surgeon and not least, the pathologist. We studied a sample consisting of 149 patients diagnosed with basal cell carcinoma at the level of the cephalic end and neck, all of them undergoing surgery - surgery individualized for each case. Some cellular and molecular modifications also resulted from infecting the cells with high carcinogenic risk HPV, considered by some scientists as responsible for the developing and progression of some neoplasias, including melanocytes and non-melanocytes skin tumors.

Corresponding author: Anca Bordianu, MD; e-mail: anca.bordianu@gmail.com

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ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Claudia Florina Andreescu, Laurenta Leila Mihai, Mihaela Raescu, Mihaela Jana Tuculina, C. N. Cumpata, Doina Lucia Ghergic

Oral mucosa becomes thinner, smooth and looses stippling aspect with aging. From histological standpoint appears: narrowing and alteration of gingival epithelium, modification of epithelial-connective interface and decreasing of keratinization. However, it cannot be detected significant histological alterations in size, shape or arrangement of epithelial cells that could be endorsed to aging process. Histological studies indicate: decreasing of keratinization, regressive changes in epithelium and fibrosis in underlying connective tissue. Parakeratosis is frequent with aging because of microtraumas, in many cases is expression of permanent inflammation.

Corresponding author: Claudia Florina Andreescu, Assistant Professor, DDS, PhD; e-mail: claudia_andreescu@yahoo.com

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