Intraventricular metastatic clear cell renal carcinoma

Vol. 54 No. 2, 2013

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

I. Sava, Anca Sava, Elena Sapte, Claudia Mihailov, Gabriela Dumitrescu, I. Poeata, Florina Sava, Danisia Haba

Background: Intraventricular tumors represent a diagnostic problem, due to a wide range of differential diagnosis, with an important variability of tumoral histological types in adult and pediatric population. Patient, Methods and Results: Our case is represented by a patient, aged 48 years, without any history of significant personal pathology, accusing nausea, vomiting, and intensive headache. In the morning, he became confused, having hallucinations for a short period of time, and has accused drowsiness for several weeks. Imaging (CT and MRI) shows a neoformation in the third ventricle, accompanied by bilateral lateral ventricles dilatation, with predominantly annular enhancement. During surgery, through the middle third transcallosal interhemispheric approach, it was revealed a reddish, well-demarcated intraventricular mass, well vascularized and with a firm consistency. Final pathologic diagnosis was metastatic clear cell renal carcinoma. Initial postoperative evolution was good, and then neurological and respiratory condition worsened as a bronchopneumonia lead to patient's death in 12 days after surgery. Conclusions: Clear cell carcinoma metastasis located in the third ventricle should be taken into consideration for patients presenting a single intraventricular lesion even they have no documented primary malignancy.

Corresponding author: Anca Sava, MD, PhD; e-mail: dr_anca_sava@yahoo.com

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