Micromolecular multiple myeloma with chronic kidney failure in a young female patient on continuous hemodialysis

Vol. 54 No. 1, 2013

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Ionela Rotaru, M. Badea, Alina Daniela Tanase, Camelia Foarfa

The maximum incidence of multiple myeloma appears in the 6th-7th decade of life and although the number of patients aged les than 60 years is increasing in recent years, the diagnosis of a monoclonal gammopathy in a young patient, under the age of 40 years remains a rarity. Literature data cite an incidence of approximately 2.2% in patients less than 40-year-old and an incidence of 0.3% in patients less than 30-year-old of all cases diagnosed with multiple myeloma. We present the case of a 32-year-old patient, being on continuous hemodialysis for chronic kidney failure for about a year, at the Hematology Clinic of Craiova, Romania. We investigate the origin of a serum monoclonal component revealed when performing serum protein electrophoresis. Bone marrow examination revealed the presence of a plasma cell infiltrate of 18%, which associated with the presence of a serum monoclonal component and in the conditions of renal failure as a complication of the disease, has allowed the diagnosis of multiple myeloma.

Corresponding author: Ionela Rotaru, Assistant Professor, MD; e-mail: rodirot@yahoo.com

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