Histopathological and immunohistochemical study of laterocervical lymph node metastases of unknown primary origin
Vol. 53 No. 2, 2012
ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY
Ramona Denise Malin, Elena Ionita, I. Osman, Carmen Aurelia Mogoanta, Luminita Cioroianu, S. Ciolofan, F. Anghelina, Madalina Enachescu
In this study, we examined histopathologically and immunohistochemically 24 cases of laterocervical lymph node metastases with unknown primary origin. For immunohistochemical study, we used a large panel of antibodies represented by CK7, CK19, CK20, CKAE1/AE3, CK34betaE12, TTF1, HBME-1, CEA, MUC5AC and EBV. In the cases studied tumors accompanied by seemingly primitive adenopathies were located in the thyroid, lung, esophagus, stomach, rhinopharynx, hypopharynx, oropharynx and larynx.
Corresponding author: Ramona Denise Malin, MD; e-mail: ramona_denise@yahoo.com
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