Primary malignant non-Hodgkin's lymphomas of salivary glands

Vol. 50 No. 4, 2009

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Alexandra Faur, Elena Lazar, Marioara Cornianu, Alis Dema, Codruta Lazureanu, Anca Muresan, Sorina Taban

We evaluated the medical record of patients with salivary gland neoplasms diagnosed at Timisoara City Hospital from 2002 to 2009. A study has been carried out for seven years on 204 cases of salivary gland tumors and only two cases of salivary gland lymphomas were diagnosed. The two cases were females of 71- and 49-year-old, respectively. The formalin-fixed paraffin-embedded tissue samples were cut in 4 micrometers thick sections and stained with Hematoxylin and Eosin. The primary monoclonal antibodies for the immunohistochemical analysis were the followings: LCA (2B11, Dako), CD20 (L26, Dako), cytokeratin (MNF116, Dako), p53 (DQ-7, Dako), and PCNA (PC-10, Dako). The histopathology and immunohistochemistry suggested in the first case a low-grade diffuse large B-cell mucosa associated lymphoid tissue lymphoma and in the second case a high-grade extranodal marginal zone B-cell lymphoma.

Corresponding author: Alexandra Faur, MD, PhD, e-mail: alexandra_pantu@yahoo.com

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