Tuberous sclerosis complex: report of two intrafamilial cases, both in mother and daughter

Vol. 50 No. 1, 2009

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Daniela Dumitrescu, E. F. Georgescu, Mihaela Niculescu, Cristiana Iulia Dumitrescu, S. S. Mogoantă, Iuliana Georgescu

Tuberous sclerosis complex (TSC) is a multisystem syndrome characterized by neurological symptoms and tumors in multiple organs including kidney, brain, skin, eyes, heart and lung. Kidney and brain are the two most frequently affected organs in TSC. TSC is an autosomal disorder with extensive clinical variability. We described TSC in a family at a mother and her daughter. We emphasized the importance of Computed Tomography in the discovery of some asymptomatic organic involvement as bilateral renal angiolipoma in the mother.

Corresponding author: Daniela Dumitrescu, MD, PhD, e-mail: daniela.dumitrescu@gmail.com

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