Neural granular cell tumor. A case report

Vol. 49 No. 1, 2008

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

C. Suciu, Anca Maria Cîmpean, M. Raica

It is presented the case of an old female with a solitary tumor at the level of the thorax. The specimen was processed using the routine histological technique and slides were stained with conventional morphologic, histochemical and immunohistochemical methods. On Hematoxylin-Eosin stained slides were noticed large cells with acidophilic cytoplasm, with granular pattern. S100 protein was intensely expressed in all tumor cells and neuron specific enolase was moderate positive. CD68 positive reaction was considered the expression of lysosomes accumulation in the cytoplasm of tumor cells. Histological and immunohistochemical findings are consistent with the diagnosis of neural granular cell tumor.

Corresponding author: Cristian Suciu, MD, e-mail: cristian_suciu@yahoo.com

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