Conservative treatment of borderline ovarian tumors: a retrospective study

Vol. 64 No. 2, 2023


Constantin-Cristian Vaduva, Carmen Constantinescu, Mihaela Tenovici, Lidia Boldeanu, Anca-Maria Istrate-Ofiteru

Borderline ovarian tumors (BOTs) are a group of tumors with histological aspects and intermediate biological evolution between benign and malignant tumors, characterized by epithelial proliferation, lack of stromal invasion and nuclear atypia. BOTs account for approximately 10-15% of epithelial ovarian carcinomas. The interest in fertility preservation is very important as most BOTs are diagnosed in patients less than 40 years of age. Since borderline tumors occur in young, fertile women, the therapeutic approach depends on both staging and the need to preserve ovarian function and fertility. Treatment of BOT is primarily surgical, but recently fertility-preserving surgery has become more important. If infertility persists, ovarian induction or in vitro fertilization (IVF) may be suggested in selected cases.

Corresponding author: Constantin-Cristian Vaduva, Associate Professor, MD, PhD; e-mail:; Lidia Boldeanu, Lecturer, MD, PhD; e-mail:

DOI: 10.47162/RJME.64.2.03 Download PDF
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