Primary thyroid angiosarcoma in a non-endemic region - a rare case

Vol. 61 No. 1, 2020

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Adrian Daniel Tulin, Adelaida Avino, Laura Raducu, Florentina Raluca Tulin, Ovidiu Stiru, Andra-Elena Balcangiu-Stroescu, Delia Timofte, Maria Daniela Tanasescu, Daniela-Gabriela Balan, Cristian-Radu Jecan, Dorin Ionescu

Thyroid angiosarcoma (AS) is a specific type of vascular tumor that arises from the endothelial cells, being highly aggressive, with increased recurrence rates and metastasis. It is characterized by positive endothelial markers and co-positive markers for cytokeratins and epithelial membrane antigen. We are describing the case of a 76-year-old patient who presented to the hospital for dyspnea and asthenia. The clinical and paraclinical investigations confirmed the presence of a right large thyroid nodule, which turned out positive at immunostaining for AS. Even if thyroid AS is a rare type of tumor, mainly described in the Alps, one has to take into account that it can evolve in any other regions and should be considered as a differential diagnosis.

Corresponding author: Laura Raducu, Lecturer, MD, PhD; e-mail: raducu.laura@yahoo.com; Maria Daniela Tanasescu, Assistant Professor, MD, PhD; e-mail: tanasescu2007@yahoo.com

DOI: 10.47162/RJME.61.1.32 Download PDF