Vagus nerve schwannoma in the parapharyngeal space: surgical, histological and immunohistochemical aspects. A case report

Vol. 56 No. 1, 2015


Vlad Andrei Budu, Ioan Alexandru Bulescu, Cristiana Gabriela Popp, Bogdan Constantin Mocanu, Carmen Aurelia Mogoanta

Tumors of the parapharyngeal space are rare accounting approximately for 0.5% of all head and neck tumors. In the retrostyloid space, schwannomas are a more common finding, in contrast to other tumors. Usually, they present with a variety of slight symptoms until they grow in size and compress surrounding organs. Surgical treatment of parapharyngeal space tumors is difficult; due to the anatomical complex area, they develop in, and include several approaches, according to its size and relations. In this paper, we present a case of a 63-year-old female with a vagus nerve schwannoma in the parapharyngeal space. Beside the surgical difficulties, the resected tumor had a peculiar histopathological aspect (large areas of degeneration and atypia and little typical palisading) that compelled a thorough histological and immunohistochemical evaluation for positive and differential diagnosis.

Corresponding author: Ioan Alexandru Bulescu, MD, PhD candidate; e-mail:

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