Oral mucosa self-graft in a patient with invasive conjunctival melanoma: a case report

Vol. 55 No. 4, 2014

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Maria Rodica Manescu, Maria Balasoiu, Monica Mihaela Craitoiu, Stefania Craitoiu, Cristiana Eugenia Simionescu, Veronica Sfredel, Sorin Nicolae Dinescu, Mihaela Niculescu, Marian Burcea, Andrei-Theodor Balasoiu, Carmen Luminita Mocanu

Conjunctival melanoma is a rare tumor, while malignant melanoma of the uveal tract is the most common primary intraocular tumor in adults. The authors highlighted the case of a 68-year-old male patient presented in June 2011 in the Ophthalmology Clinic of the Emergency County Hospital of Craiova, Romania, accusing foreign body sensation and the appearance of a tumor in the lower fornix of his right eye. The patient was clinically and paraclinically investigated, and clinically diagnosed with de novo malignant melanoma. The tumor was surgically excised and the lower fornix reconstructed with oral mucosa self-graft. Histopathological diagnosis was de novo, invasive, ulcerated malignant melanoma of the conjunctiva. Ki-67 immunohistochemical staining was also performed. After surgery, the patient was sent to the Oncology Department for specific treatment. Despite the histological poor prognosis factors present in our patient, two years after surgery and chemotherapy, the patient had no clinical sign of local or distance recurrent disease. Continuous ophthalmologic and oncological surveillance is necessary.

Corresponding author: Maria Balasoiu, Associate Professor, MD, PhD; e-mail: balasoiu.maria@yahoo.com

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