Correlations between cyto-histopathological tissue changes at the dental implant interface and the degree of surface processing

Vol. 55 No. 2 Suppl., 2014
This supplement was not sponsored by Outside Organizations.


Raluca Monica Comaneanu, Horia Mihail Barbu, Costin Coman, Florin Miculescu, Luminita Chiutu

The bone tissue is a specialized connective tissue adapted for support and protection. The bone physiology is balanced by the interaction between mechanical and metabolic factors. Current research focuses on the bone remodeling process after the insertion of dental implants, because, after the primary healing of the wound caused by the creation of the new alveolus, the proliferation and differentiation of the osteoblasts and fibroblasts will tip the balance of the healing pattern toward bone regeneration or fibrous encapsulation. Knowing and identifying the components of the connective and bone tissue prior to implant placement, researchers are investigating the quality and quantity of the bone matrix and the physiological stages of bone generation and resorption to improve the bone-implant interface. Our research included nine dental implant failures, without prosthetic supra-structures, immediately loaded or loaded after osseointegration. The analyzed samples were from the BIOMAT Research Center, Politehnica University of Bucharest, Romania, and experienced different modalities of surface preparation. Comparative analysis of the tissue at the bone-implant interface was investigated by scanning electron microscopy.

Corresponding author: Horia Mihail Barbu, Lecturer, DDS, PhD; e-mail:

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Isabela-Magdalena Draghici, Dragos-Constantin Luca, Maria-Delia Popescu, Liviu Draghici

The pediatric patient is often difficult to diagnose, especially since the surgical pathology is tumoral. Establishing the histopathological diagnosis of a tumor, staging of a disease and certifying the existence of rare pediatric affections are three of the motives for which the specialists frequently appeal to an exploratory laparoscopy, accompanied by biopsy procedures. The paper presents the laparoscopic biopsy experience of the team from the Department of Pediatric Surgery, Maria Sklodowska Curie Emergency Clinical Hospital for Children, Bucharest, Romania. From 2000 to 2013, 95 such procedures were performed (7.76% of a total of 1224 laparoscopic interventions). In many cases, the laparoscopy had an exclusive diagnostic purpose, of whose success has been primarily responsible the targeted biopsy. Current issues are discussed, centered on the most advanced technologies used in minimally invasive approach of pediatric malignancies, referring to the effect of minimizing the possible complications that can arise from this type of intervention. The authors concluded that laparoscopic technique is the method of choice in comparison to other ways of biopsy (classical surgery, ultrasound guidance, tomography, etc.), and it is characterized by a high diagnostic value.

Corresponding author: Isabela-Magdalena Draghici, Lecturer, MD, PhD; e-mail:

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