Synchronous diagnosis of signet ring cell colon carcinoma and transitional carcinoma of the left distal ureter

Vol. 54 No. 3 Suppl., 2013
This supplement was not sponsored by Outside Organizations.

ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

Liliana Streba, Corina Gruia, S. S. Mogoanta, P. Mitrut, Letitia Adela-Maria Streba, Adriana Bold

The presence of synchronous multiple primary carcinomas, although recognized, remains very uncommon. Their etiopathogeny is unclear. The wide spread of imaging techniques currently facilitates diagnosis of simultaneous tumors. We present the rare case of a signet ring cell colon carcinoma coexisting with a transitional cell carcinoma (TCC) of the ureter, which debuted with symptoms of intestinal obstruction in a 75-year-old male patient, with no prior relevant history. Computed tomography showed signs of a tumor mass on the transverse colon, as well as left hydronephrosis with a tumor in the lower third of the ureter, which prompted for immediate emergency surgery. After the appropriate surgical maneuvers, tissue collected from both tumors underwent usual histological preparation and Hematoxylin-Eosin staining, as well as multiple immunostaining with a complex panel of markers. The patient had a favorable postoperative course and during a six-month follow-up, we did not detect any signs of illness.

Corresponding author: Letitia Adela-Maria Streba, Associate Professor, MD, PhD, MSc; e-mail: letitiastreba@yahoo.com

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ROMANIAN JOURNAL of MORPHOLOGY and EMBRYOLOGY

M. Ceausu, R. A. Ionescu, B. Malinescu, M. C. Rusu, S. Hostiuc, D. Dermengiu

Myocardial bridging (MB) is defined as the presence of an intramural course of a coronary artery, most likely caused by a defect in resorption of the musculature that encircles the epicardial arteries during morphogenesis. We present a case of the young man who died suddenly while playing professional football and whose cause of death was acute myocardial infarction associated with multiple myocardial bridges (1.8 cm on the anterior interventricular artery, 1.3 cm on the circumflex artery, and an intramyocardial trajectory of the posterior interventricular artery), and discuss the causes of death and possible consequences of this pathology.

Corresponding author: Mugurel Constantin Rusu, Senior Lecturer, MD, PhD; e-mail: anatomon@gmail.com

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